American Cancer Society Headquarters & Corporate Office

About American Cancer Society

The American Cancer Society, commonly known as ACS, is one of the largest nonprofit cancer-fighting organizations in the United States. It was founded in 1913 in New York City by 10 physicians and five laypeople under the original name American Society for the Control of Cancer. Its early mission was to increase public awareness about cancer at a time when the disease was rarely discussed openly. The organization adopted the American Cancer Society name in 1945 and expanded into research funding, patient assistance, cancer education, prevention, early detection, advocacy, and community support.

Today, ACS works across three major mission areas: cancer research, patient support, and advocacy. Its services include a 24/7 cancer helpline, Hope Lodge lodging programs, transportation assistance, cancer information, online support resources, prevention and screening education, research grants, fundraising programs, and support for patients, caregivers, and families. ACS also publishes major scientific resources, including its annual Cancer Facts & Figures report.

The organization remains a tax-exempt nonprofit rather than a publicly traded corporation, so it has no conventional corporate owner or shareholders. Current executive leadership is headed by Shane Jacobson, Chief Executive Officer, while the volunteer Board of Directors provides governance. ACS has also changed its fiscal-year structure: beginning in 2025, the organization shifted from a calendar-year reporting period to a fiscal year running from April 1 through March 31.

American Cancer Society Headquarters & Corporate Office Address

Current Headquarters

American Cancer Society, Inc.
250 Williams Street NW
Atlanta, GA 30303
United States

Current ACS state fundraising notices explicitly identify 250 Williams Street NW, Atlanta, GA 30303 as the organization’s Global Headquarters. This is the best current address to use when identifying the organization’s headquarters rather than older addresses found on legacy directories.

Corporate / Business Office

ACS currently also publishes the following business address for tax and administrative purposes:

270 Peachtree Street NW, Suite 1300
Atlanta, GA 30303
United States

The official Contact Us page specifically labels this the Business Address, while distinguishing it from the separate donation-mailing address.

Mailing Address

For donations by mail:

American Cancer Society
P.O. Box 6704
Hagerstown, MD 21741
United States.

Other Important Address

Privacy-related correspondence may currently be sent to:

American Cancer Society, Inc.
Attn: Security and Privacy Requests
270 Peachtree Street, Suite 1300
Atlanta, GA 30303.

Former / Historical Headquarters

Older American Cancer Society materials and third-party directories may show earlier Atlanta office addresses. For current headquarters purposes, 250 Williams Street NW should be treated as the verified Global Headquarters, while 270 Peachtree Street NW, Suite 1300 is the current business/tax address.

Quick Information

Corporate Phone Number

404-320-3333

ACS publishes this number with its General Counsel and Atlanta headquarters information.

Customer Service Number

1-800-227-2345

This is the primary American Cancer Society helpline and public support number, available 24 hours a day, 7 days a week.

Corporate Office Address

270 Peachtree Street NW, Suite 1300, Atlanta, GA 30303

Headquarters Address

250 Williams Street NW, Atlanta, GA 30303

Email

ACS does not publish one universal ordinary customer-service email.

Current verified specialized emails include:

Privacy: acs.dpo@cancer.org
Privacy Requests: privacyrequest@cancer.org
Legal: LegalDepartment@cancer.org.

Industry

Nonprofit Healthcare, Cancer Research, Patient Support, Health Education, Advocacy and Charitable Services

Founded

1913

Number of Employees

ACS does not currently publish one simple up-to-date companywide employee headcount on its main public corporate pages. Its employment platform confirms an active nationwide professional workforce, but an exact current total should not be inferred from job postings.

Number of Volunteers / Community Reach

ACS operates nationally through employees, volunteers, donors, researchers, healthcare partners, events, and community-based programs. Current public materials continue to describe ACS as one of the world’s largest voluntary health organizations.

Corporate Office Hours

The Global Headquarters does not publish standard public walk-in office hours.

The Cancer Helpline is available 24/7, while live online chat is available on weekdays.

Website

https://www.cancer.org/

Careers Page

https://jobs.cancer.org/

American Cancer Society Products & Services

24/7 Cancer Helpline

ACS operates a nationwide cancer helpline at 1-800-227-2345. Trained cancer information specialists provide general cancer information, help locate resources, explain available patient programs, and support patients, caregivers, and family members throughout the cancer journey.

Cancer Information and Education

ACS provides detailed educational information covering cancer types, symptoms, risk factors, diagnosis, treatment options, side effects, prevention, screening, survivorship, and caregiving. Its information is intended to help patients understand their options and prepare for discussions with healthcare professionals.

Cancer Research

The American Cancer Society funds and conducts cancer research covering prevention, detection, treatment, survivorship, epidemiology, health equity, and other scientific areas. Research funding has been part of the organization’s core mission since the mid-20th century.

Cancer Facts & Figures

ACS publishes Cancer Facts & Figures annually, providing national and state estimates of cancer cases and deaths along with current information on incidence, mortality, survival, prevention, and screening. The publication has been issued annually since 1951.

Hope Lodge

Hope Lodge provides qualifying cancer patients and caregivers with a place to stay when treatment requires traveling away from home. The program is designed to reduce lodging costs and make extended treatment more accessible.

Transportation Assistance

ACS helps eligible patients identify transportation resources for cancer treatment. Availability differs by community, but ACS can connect callers with rides, transportation programs, and other local resources through its helpline.

Patient Resource Navigation

Cancer information specialists help patients and caregivers identify relevant programs and resources based on their location and needs. This can include transportation, lodging, emotional support, financial-resource referrals, and community services.

Online Support Communities

ACS provides digital support resources for cancer patients, survivors, and caregivers. These tools help users connect with others facing similar experiences and locate trusted educational information.

Cancer Prevention Education

ACS provides guidance about reducing cancer risk through tobacco avoidance, healthy lifestyle choices, screening, vaccinations where applicable, and awareness of known cancer risks.

Screening and Early Detection Guidance

ACS publishes screening recommendations and educational materials for cancers such as breast, colorectal, cervical, lung, and prostate cancer. These resources are designed to help individuals discuss appropriate screening with healthcare providers.

Relay For Life

Relay For Life is one of ACS’s best-known fundraising and community-engagement programs. Local events bring survivors, caregivers, families, volunteers, and supporters together to raise funds and recognize people affected by cancer.

Making Strides Against Breast Cancer

Making Strides Against Breast Cancer events raise funds and awareness supporting ACS breast-cancer research, education, and patient services.

Donations

ACS accepts one-time donations, monthly giving, memorial gifts, tribute gifts, planned gifts, and other charitable contributions. Donations can be made online, by phone, or by mail.

Volunteer Opportunities

ACS offers volunteer opportunities connected with fundraising, patient programs, events, advocacy, Hope Lodge, and community outreach.

Cancer Advocacy

Through the related American Cancer Society Cancer Action Network, the broader ACS organization advocates for public policies addressing cancer prevention, screening, research funding, access to care, affordability, and health equity.

American Cancer Society Corporate Phone Numbers

Corporate Phone Number

404-320-3333

Corporate Headquarters Number

404-320-3333

Headquarters Number

For public assistance, ACS generally directs callers to:

1-800-227-2345

Corporate Office Number

404-320-3333

Customer Service Number

1-800-227-2345

Customer Support Number

1-800-227-2345

Toll-Free Number

1-800-227-2345

Cancer Helpline

1-800-227-2345

Available 24/7.

Donation Number

1-800-227-2345

Donation specialists are available through this line, with dedicated donation-assistance hours also published by ACS.

Sales Number

Not applicable.

ACS is a nonprofit charitable organization rather than a commercial retail company.

Billing Number

No universal public billing number is separately published.Donation or transaction questions can begin through 1-800-227-2345.

Regional Office Number

ACS maintains community and regional operations, but no single nationwide regional-office phone applies to every location.

Branch Office Number

Local office contacts vary by community.

International Number

ACS does not publish one universal international customer-service number.

Emergency / After-Hours Number

The Cancer Helpline remains available 24/7 at:

1-800-227-2345

It is not an emergency medical service.

Investor Relations Number

Not applicable.

ACS has no public shareholders.

Media / Press Number

ACS media contacts vary by topic and region. Media inquiries are handled through its pressroom and communications staff.

Human Resources Number

No universal public HR number is prominently published.

Careers

https://jobs.cancer.org/

Privacy / Security Hotline

1-800-539-7202

This independently managed hotline is available 24/7 for suspected privacy/security breaches or potentially fraudulent activity involving ACS constituent information.

How to Reach a Real Person at American Cancer Society

The best general number for reaching a real American Cancer Society representative is 1-800-227-2345. The line is staffed around the clock by trained cancer information specialists who can assist with cancer information, resource referrals, volunteer questions, donation questions, event information, and many other public inquiries. Before calling, have the patient’s ZIP code, cancer type if relevant, treatment location, specific resource need, or donation information available so the representative can route the inquiry efficiently.

For legal or corporate matters, use the Atlanta corporate offices rather than the Cancer Helpline. Privacy inquiries should use acs.dpo@cancer.org, while formal legal notices can use the General Counsel contact at 250 Williams Street NW, Atlanta, GA 30303. For local programs such as Hope Lodge, transportation assistance, events, or community services, the helpline can identify the appropriate local resource.

How to File a Complaint Against American Cancer Society

Complaints against ACS can involve donations, fundraising communications, volunteer experiences, privacy, events, local programs, website issues, charitable solicitations, or interactions with employees or representatives. Before escalating, collect donation receipts, transaction records, emails, dates, names of representatives, event information, and copies of any previous correspondence.

Step 1: Contact Customer Service

Call 1-800-227-2345 and explain the concern clearly. Provide the relevant donation, event, program, volunteer, or contact information and ask the representative to document the issue. For donation problems, have the payment date, amount, payment method, and donor name available. Request clarification about what action will be taken and retain any reference information.

Step 2: Contact the Relevant Department

If the complaint relates to a specific function, use the department responsible for it. Privacy matters should be directed to acs.dpo@cancer.org or privacyrequest@cancer.org, while legal concerns can be directed to the ACS Legal Department. Local program complaints should be routed to the office or program responsible for the activity.

Step 3: Request Supervisor or Management Review

If the first response is insufficient, request review by a supervisor or program manager. Give the reviewer a concise timeline, identify the representatives already contacted, and explain what remains unresolved. Clearly state the resolution you are seeking, such as correcting a donation record, stopping communications, reviewing program conduct, or addressing a privacy concern.

Step 4: Use the Company’s Written Complaint Channel

Submit the complaint in writing so there is a clear record. Privacy complaints may be emailed to the Privacy Officer, while other matters can be sent through ACS contact channels or mailed to the relevant business address. Include supporting documents and copies rather than original receipts.

Step 5: Contact Corporate Headquarters

For a serious unresolved organization-level matter, write to American Cancer Society, Inc., 250 Williams Street NW, Atlanta, GA 30303. Provide your full contact information, prior case history, dates, supporting documents, and a concise description of the resolution requested.

Step 6: Use the Specialized Complaint or Dispute Department

Suspected privacy/security breaches or potentially fraudulent activity can be reported to the independent hotline at 1-800-539-7202. Legal matters may be addressed to the General Counsel, while data-privacy appeals can be directed to the ACS Privacy Officer.

Step 7: File With the Appropriate Regulator

If the complaint concerns charitable solicitation or nonprofit governance, the relevant state Attorney General, Secretary of State, charity regulator, or other state agency may have jurisdiction. The appropriate regulator depends on the state where the donor resides and the nature of the complaint.

Step 8: Use Consumer Protection or Financial Dispute Options

For a disputed credit-card donation or unauthorized transaction, contact the card issuer or payment provider after first attempting resolution with ACS. Consumer-protection authorities may also be appropriate if the complaint involves misleading solicitation, unauthorized charges, or another consumer issue.

Step 9: Consider Formal Legal or Arbitration Procedures

For serious unresolved legal disputes, obtain independent legal advice before taking formal action. Review any applicable donation, website, privacy, event, or service terms to determine what dispute process applies. Preserve all records, receipts, correspondence, screenshots, and written responses before pursuing formal remedies.

 

Kevin

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